Pre-interpretation review and virtual gene panel assignment

Specification of analysis parameters including penetrance settings and panel assignment is carried out by GLH or Ordering Entity staff in the NGIS test order system. For each clinical indication, a default virtual panel and penetrance setting are attributed, but these can be modified according to local SOPs. Please see the Transcribing Whole Genome Sequence Test Requests in the NGIS User Guide for details of how to set these parameters. If the penetrance setting, disease status or panel assignment have been set incorrectly, please consult the Cancelling or Updating a Test Request or Patient Record in the NGIS SOP document for guidance.